- sc_griffith ( @sc_griffith@awful.systems ) English17•10 months ago
I’ve now talked to some pretty well-qualified bio PHDs with expertise in stem cells, gene therapy, and genetics. While many of them were skeptical, none of them could point to any part of the proposed treatment process that definitely won’t work.
absolutely classic crank shit
- AcausalRobotGod ( @AcausalRobotGod@awful.systems ) English15•10 months ago
I talked to some pretty well-qualified math PhDs with expertise in analytic number theory, algebraic number theory, and geometric number theory. While many of them were skeptical, none of them could point to any part of my proposed proof of Fermat’s Last Theorem that definitely won’t work.
- sc_griffith ( @sc_griffith@awful.systems ) English15•10 months ago
I’m a mathematician and this is exactly what I was imagining lmao
- AcausalRobotGod ( @AcausalRobotGod@awful.systems ) English12•10 months ago
so you’re saying I successfully simulated your thoughts, eh???
- sc_griffith ( @sc_griffith@awful.systems ) English11•10 months ago
wow. the ai really is going to get out of the box. if you as a lemmy poster can do this imagine how easy it will be for gpt5
- AcausalRobotGod ( @AcausalRobotGod@awful.systems ) English10•10 months ago
Wow, I mean, look at who you’re actually talking to here: I’m acausally reaching back in time to post this.
- sc_griffith ( @sc_griffith@awful.systems ) English9•10 months ago
what rats think their nightmare is: robot god condemns them to hell for eternity
what their actual nightmare is: robot god shitposts on sneerclub
- AcausalRobotGod ( @AcausalRobotGod@awful.systems ) English6•10 months ago
And they’re already living it!
- self ( @self@awful.systems ) English7•10 months ago
ah, the long-awaited activitypub to future simulated hell API integration
isn’t that all fediverse software
- locallynonlinear ( @locallynonlinear@awful.systems ) English6•10 months ago
I don’t think we would work out…
So you’re saying I have a chance?
- swlabr ( @swlabr@awful.systems ) English16•10 months ago
Hmm, how significant are we talking
predicted IQ of about 900
lol
- Amoeba_Girl ( @Amoeba_Girl@awful.systems ) English16•10 months ago
In the course of my life, there have been a handful of times I discovered an idea that changed the way I thought about the world. The first occurred when I picked up Nick Bostr
Alright thank you that’s enough.
- -dsr- ( @dashdsrdash@awful.systems ) English15•10 months ago
Genetically altering IQ is more or less about flipping a sufficient number of IQ-decreasing variants to their IQ-increasing counterparts. This sounds overly simplified, but it’s surprisingly accurate; most of the variance in the genome is linear in nature, by which I mean the effect of a gene doesn’t usually depend on which other genes are present
Contradicted by previous text in the same article (diabetes), not to mention have you even opened a college-level genetics text in the last decade?
Anyway, I would encourage these people to flip their own genome a lot, except that they probably won’t take the minimum necessary precautions of doing so under observation in isolation. “Science is whatever people in white coats say it is, and I bought a nice white coat off Amazon!”
- flere-imsaho ( @mawhrin@awful.systems ) English12•10 months ago
most of the variance in the genome is linear in nature, by which I mean the effect of a gene doesn’t usually depend on which other genes are present
that person seems homeschooled on absolute bullshit; basic high school biology course thirty-odd years ago was saying otherwise.
- self ( @self@awful.systems ) English11•10 months ago
that person seems homeschooled on absolute bullshit
the yudkowsky tradition! cause skimming a book and reconstructing the rest of the knowledge on your gut feelings is a perfectly good substitute for going to fucking school, Eliezer
- Umbrias ( @Umbrias@beehaw.org ) English6•10 months ago
Meanwhile actual discussions about biotech are more like
“Is it feasible to get widespread changes in an organism we want or are biological systems hopelessly and fundamentally complex making this impossible?”
The contrast amuses me.
- AcausalRobotGod ( @AcausalRobotGod@awful.systems ) English14•10 months ago
LOL – looking at the comments: “can somebody open a manifold market so I can get a sense of the probabilities?”
- GorillasAreForEating ( @GorillasAreForEating@awful.systems ) English7•10 months ago
And yet the market is said to be “erring” and to have “irrationality” when it disagrees with rationalist ideas. Funny how that works.
- self ( @self@awful.systems ) English9•10 months ago
It seems pretty obvious to me, and probably to many other people in the rationalist community, that if AGI goes well, every business that does not control AI or play a role in its production will become virtually worthless. Companies that have no hope of this are obviously overvalued, and those that might are probably undervalued (at least as a group).
asking the important questions: if my god materializes upon the earth, how can I use that to make a profit?
- locallynonlinear ( @locallynonlinear@awful.systems ) English10•10 months ago
Question: if the only thing that matter is using AGI, what powers the AGI? Does the AGI produce net positive energy to power the continued expansion of AGI? Does AGI break the law of conservation because… if it didn’t, it wouldn’t be AGI?
- self ( @self@awful.systems ) English8•10 months ago
n-nuh uh, my super strong AI god will invent cold fusion and nanotechnology and then it won’t need any resources at all, my m-m-mathematical calculations prove it!
ok but how will the AI exist and exponentially multiply in a world where those things don’t already exist?
y-you can’t say that to me! I’m telling poppy yud and he’s gonna bomb all your data centers!
- shinigami3 ( @shinigami3@awful.systems ) English13•10 months ago
starts reading
looks at the scrollbar size
nope
- GorillasAreForEating ( @GorillasAreForEating@awful.systems ) English13•10 months ago
the cell’s ribosomes will transcribe mRNA into a protein. It’s a little bit like an executable file for biology.
Also, because mRNA basically has root level access to your cells, your body doesn’t just shuttle it around and deliver it like the postal service. That would be a major security hazard.
I am not saying plieotropy doesn’t exist. I’m saying it’s not as big of a deal as most people in the field assume it is.
Genes determine a brain’s architectural prior just as a small amount of python code determines an ANN’s architectural prior, but the capabilities come only from scaling with compute and data (quantity and quality).
When you’re entirely shameless about your Engineer’s Disease
- skillissuer ( @skillissuer@discuss.tchncs.de ) English10•10 months ago
If not for that pesky FDA, rats would develop the most bizzare case of liver failure that medicine has ever seen and took over the world with their superior intellect, any day now, you’ll see
- mayooooo ( @MayonnaiseArch@beehaw.org ) English8•10 months ago
Well he really could use a boost lol
he’s even better in the comments, absolutely unhinged
- AcausalRobotGod ( @AcausalRobotGod@awful.systems ) English6•10 months ago
Maybe he’ll get to the point where he thinks you could do it by changing mouth bacteria to CRISPR your shit. Cure gum disease at the same time!
- bitofhope ( @bitofhope@awful.systems ) English8•10 months ago
Credit where it’s due, I appreciate them leading with a TL;DR link to a summary. Unfortunately the summary was also too long and I didn’t read it. I’m happy for you though. Or sorry it happened.
- Soyweiser ( @Soyweiser@awful.systems ) English7•10 months ago
LLM’s are great you doubters, look this guy even used it to get unshadowbanned on twitter.
Re the subject at hand 250+ upvotes oof. And once I again I feel the desire to write a 'gene editing to improve intelligence is immoral because of the higher depression risk that correlates with higher intelligence. But that would backfire very quickly (esp if we hook into other reasons why very smart people with no economic resources might even be extra depressed and poof we are back at eugenics and keeping the
Morlockspoor away from intelligence improvements).Vague association with eugenics make some academics shy away
This guys profile:
currently doing independent research on gene therapy with an emphasis on intelligence enhancement.
Gosh. (I honestly had not noticed these 2 quotes before I mentioned my trollpost + risk).
- skillissuer ( @skillissuer@discuss.tchncs.de ) English8•10 months ago
that’s just brave new world with extra steps
- Soyweiser ( @Soyweiser@awful.systems ) English6•10 months ago
I have thought that for the distopia a lot of the right fears brave new world fits a lot better than 1984. But that is unrelated to this.
- carlitoscohones ( @carlitoscohones@awful.systems ) English7•10 months ago
I clicked the original LW link (not the archive link) and got a malware warning.
it was warning you the page contained lesswrong rationalism
- carlitoscohones ( @carlitoscohones@awful.systems ) English4•10 months ago
I just tried it again. it’s my Orbi wi-fi thing, every time I follow a link to LW - “Orbit has blocked a malware attempt.”
- self ( @self@awful.systems ) English4•10 months ago
maybe whoever wrote the heuristic is also an anti-fan of rationalism and this is the form their sneering took
- skillissuer ( @skillissuer@discuss.tchncs.de ) English3•10 months ago
Ripperdocs don’t want you to know this simple trick [click here]
- Abe Froman ( @pikesley@mastodon.me.uk ) 4•10 months ago
@dgerard god almighty there’s *so much of it*
- HubertManne ( @HubertManne@kbin.social ) 3•10 months ago
I mean personally I would fix things that are broken first. The last thing I might want to edit is anything nerve related and even then problems before enhancements. Im pretty happy with my intellect level and could not see messing with that unless it clearly was needed in the sense that I fell below one standard deviation of average intellect.