I start: the most important thing is not the desktop, it’s the package manager.

  • Always put your filesystems in an LVM volume (and in general, partition disks with LVM rather than partition tables)! You never know when you might need to combine multiple disks, make a snapshot, add redundancy, or transfer to another disk without unmounting. But it’s very difficult to format a block device as LVM once you can’t erase its contents.

    Make your /boot partition at least 500MiB.

    Leave at least 1GiB of free space at the beginning of every disk. You never know when you might need to add EFI and boot partitions to that disk. And again, it’s very difficult to do after the fact.