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Lee Duna ( throws_lemy@lemmy.nz )  to Europe@feddit.deEnglish · 3 years ago

U.K. cracks down on synthetic opioid 10 times stronger than fentanyl causing overdoses in Europe

www.cbsnews.com

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U.K. cracks down on synthetic opioid 10 times stronger than fentanyl causing overdoses in Europe

www.cbsnews.com

Lee Duna ( throws_lemy@lemmy.nz )  to Europe@feddit.deEnglish · 3 years ago
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As authorities clamp down on fentanyl distribution and the amount of heroin produced in Afghanistan decreases under the Taliban, criminal enterprises have turned to a deadly alternative option.
  • sqgl ( sqgl@beehaw.org ) 
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    3 years ago

    What does it mean for drug B to be X times stronger than drug A? Is it per milligram? Per LD50?

    • pedroapero ( pedroapero@lemmy.ml ) 
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      3 years ago

      That would be the required dosage to get a regular hit (or to feel something maybe)

      • sqgl ( sqgl@beehaw.org ) 
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        3 years ago

        Measured by weight (mg)?

        • tryptaminev 🇵🇸 🇺🇦 🇪🇺 ( tryptaminev@feddit.de ) 
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          3 years ago

          https://en.wikipedia.org/wiki/List_of_benzimidazole_opioids

          There is the Analgetic Potency listed, which would be the weight factor. However looking at the individual compounds the numbers can vary drastically, i didnt find any LD50 information and many of them being just completely new.

          For reference Heroin has a potency of about 2 compared to Morphine and Fentanyl has a potency of about 100.

          So this is uncharted territory both in terms of potency and the compounds themselves. There exists no knowledge about the precise effects, about side effects, long term harm, addiction…

        • pedroapero ( pedroapero@lemmy.ml ) 
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          3 years ago

          Yep

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