Beehaw
  • Communities
  • Create Post
  • search
    Search
  • Login
  • Sign Up
David Gerard ( dgerard@awful.systems ) M to SneerClub@awful.systemsEnglish · 3 years ago

LW: CRISPR Will Make Me A Genius - "I don’t have a formal background in biology. And though I learn fairly quickly and have great resources like SciHub and GPT4,"

www.lesswrong.com

external-link
message-square
39
link
fedilink
24
external-link

LW: CRISPR Will Make Me A Genius - "I don’t have a formal background in biology. And though I learn fairly quickly and have great resources like SciHub and GPT4,"

www.lesswrong.com

David Gerard ( dgerard@awful.systems ) M to SneerClub@awful.systemsEnglish · 3 years ago
message-square
39
link
fedilink

archive: https://archive.is/KdzMM

alert-triangle
You must log in or # to comment.
  • sc_griffith ( sc_griffith@awful.systems ) 
    link
    fedilink
    English
    arrow-up
    17
    ·
    3 years ago

    I’ve now talked to some pretty well-qualified bio PHDs with expertise in stem cells, gene therapy, and genetics. While many of them were skeptical, none of them could point to any part of the proposed treatment process that definitely won’t work.

    absolutely classic crank shit

    • AcausalRobotGod ( AcausalRobotGod@awful.systems ) 
      link
      fedilink
      English
      arrow-up
      15
      ·
      3 years ago

      I talked to some pretty well-qualified math PhDs with expertise in analytic number theory, algebraic number theory, and geometric number theory. While many of them were skeptical, none of them could point to any part of my proposed proof of Fermat’s Last Theorem that definitely won’t work.

      • sc_griffith ( sc_griffith@awful.systems ) 
        link
        fedilink
        English
        arrow-up
        15
        ·
        3 years ago

        I’m a mathematician and this is exactly what I was imagining lmao

        • AcausalRobotGod ( AcausalRobotGod@awful.systems ) 
          link
          fedilink
          English
          arrow-up
          12
          ·
          3 years ago

          so you’re saying I successfully simulated your thoughts, eh???

          • sc_griffith ( sc_griffith@awful.systems ) 
            link
            fedilink
            English
            arrow-up
            11
            ·
            3 years ago

            wow. the ai really is going to get out of the box. if you as a lemmy poster can do this imagine how easy it will be for gpt5

            • AcausalRobotGod ( AcausalRobotGod@awful.systems ) 
              link
              fedilink
              English
              arrow-up
              10
              ·
              3 years ago

              Wow, I mean, look at who you’re actually talking to here: I’m acausally reaching back in time to post this.

              • sc_griffith ( sc_griffith@awful.systems ) 
                link
                fedilink
                English
                arrow-up
                9
                ·
                3 years ago

                what rats think their nightmare is: robot god condemns them to hell for eternity

                what their actual nightmare is: robot god shitposts on sneerclub

                • AcausalRobotGod ( AcausalRobotGod@awful.systems ) 
                  link
                  fedilink
                  English
                  arrow-up
                  6
                  ·
                  3 years ago

                  And they’re already living it!

              • self ( self@awful.systems ) 
                link
                fedilink
                English
                arrow-up
                7
                ·
                3 years ago

                ah, the long-awaited activitypub to future simulated hell API integration

                • David Gerard ( dgerard@awful.systems ) OP
                  link
                  fedilink
                  English
                  arrow-up
                  7
                  ·
                  3 years ago

                  isn’t that all fediverse software

    • locallynonlinear ( locallynonlinear@awful.systems ) 
      link
      fedilink
      English
      arrow-up
      6
      ·
      3 years ago

      I don’t think we would work out…

      So you’re saying I have a chance?

  • swlabr ( swlabr@awful.systems ) 
    link
    fedilink
    English
    arrow-up
    16
    ·
    3 years ago

    Hmm, how significant are we talking

    predicted IQ of about 900

    lol

  • Amoeba_Girl ( Amoeba_Girl@awful.systems ) 
    link
    fedilink
    English
    arrow-up
    16
    ·
    3 years ago

    In the course of my life, there have been a handful of times I discovered an idea that changed the way I thought about the world. The first occurred when I picked up Nick Bostr

    Alright thank you that’s enough.

  • -dsr- ( dashdsrdash@awful.systems ) 
    link
    fedilink
    English
    arrow-up
    15
    ·
    3 years ago

    Genetically altering IQ is more or less about flipping a sufficient number of IQ-decreasing variants to their IQ-increasing counterparts. This sounds overly simplified, but it’s surprisingly accurate; most of the variance in the genome is linear in nature, by which I mean the effect of a gene doesn’t usually depend on which other genes are present

    Contradicted by previous text in the same article (diabetes), not to mention have you even opened a college-level genetics text in the last decade?

    Anyway, I would encourage these people to flip their own genome a lot, except that they probably won’t take the minimum necessary precautions of doing so under observation in isolation. “Science is whatever people in white coats say it is, and I bought a nice white coat off Amazon!”

    • flere-imsaho ( mawhrin@awful.systems ) 
      link
      fedilink
      English
      arrow-up
      12
      ·
      3 years ago

      most of the variance in the genome is linear in nature, by which I mean the effect of a gene doesn’t usually depend on which other genes are present

      that person seems homeschooled on absolute bullshit; basic high school biology course thirty-odd years ago was saying otherwise.

      • self ( self@awful.systems ) 
        link
        fedilink
        English
        arrow-up
        11
        ·
        3 years ago

        that person seems homeschooled on absolute bullshit

        the yudkowsky tradition! cause skimming a book and reconstructing the rest of the knowledge on your gut feelings is a perfectly good substitute for going to fucking school, Eliezer

    • Umbrias ( Umbrias@beehaw.org ) 
      link
      fedilink
      English
      arrow-up
      6
      ·
      3 years ago

      Meanwhile actual discussions about biotech are more like

      “Is it feasible to get widespread changes in an organism we want or are biological systems hopelessly and fundamentally complex making this impossible?”

      The contrast amuses me.

  • AcausalRobotGod ( AcausalRobotGod@awful.systems ) 
    link
    fedilink
    English
    arrow-up
    14
    ·
    3 years ago

    LOL – looking at the comments: “can somebody open a manifold market so I can get a sense of the probabilities?”

    • GorillasAreForEating ( GorillasAreForEating@awful.systems ) 
      link
      fedilink
      English
      arrow-up
      7
      ·
      3 years ago

      And yet the market is said to be “erring” and to have “irrationality” when it disagrees with rationalist ideas. Funny how that works.

      • self ( self@awful.systems ) 
        link
        fedilink
        English
        arrow-up
        9
        ·
        3 years ago

        It seems pretty obvious to me, and probably to many other people in the rationalist community, that if AGI goes well, every business that does not control AI or play a role in its production will become virtually worthless. Companies that have no hope of this are obviously overvalued, and those that might are probably undervalued (at least as a group).

        asking the important questions: if my god materializes upon the earth, how can I use that to make a profit?

        • locallynonlinear ( locallynonlinear@awful.systems ) 
          link
          fedilink
          English
          arrow-up
          10
          ·
          3 years ago

          Question: if the only thing that matter is using AGI, what powers the AGI? Does the AGI produce net positive energy to power the continued expansion of AGI? Does AGI break the law of conservation because… if it didn’t, it wouldn’t be AGI?

          • self ( self@awful.systems ) 
            link
            fedilink
            English
            arrow-up
            8
            ·
            3 years ago

            n-nuh uh, my super strong AI god will invent cold fusion and nanotechnology and then it won’t need any resources at all, my m-m-mathematical calculations prove it!

            ok but how will the AI exist and exponentially multiply in a world where those things don’t already exist?

            y-you can’t say that to me! I’m telling poppy yud and he’s gonna bomb all your data centers!

  • shinigami3 ( shinigami3@awful.systems ) 
    link
    fedilink
    English
    arrow-up
    13
    ·
    3 years ago

    starts reading

    looks at the scrollbar size

    nope

  • GorillasAreForEating ( GorillasAreForEating@awful.systems ) 
    link
    fedilink
    English
    arrow-up
    13
    ·
    edit-2
    3 years ago

    the cell’s ribosomes will transcribe mRNA into a protein. It’s a little bit like an executable file for biology.

    Also, because mRNA basically has root level access to your cells, your body doesn’t just shuttle it around and deliver it like the postal service. That would be a major security hazard.

    I am not saying plieotropy doesn’t exist. I’m saying it’s not as big of a deal as most people in the field assume it is.

    Genes determine a brain’s architectural prior just as a small amount of python code determines an ANN’s architectural prior, but the capabilities come only from scaling with compute and data (quantity and quality).

    When you’re entirely shameless about your Engineer’s Disease

  • skillissuer ( skillissuer@discuss.tchncs.de ) 
    link
    fedilink
    English
    arrow-up
    10
    ·
    3 years ago

    If not for that pesky FDA, rats would develop the most bizzare case of liver failure that medicine has ever seen and took over the world with their superior intellect, any day now, you’ll see

  • mayooooo ( MayonnaiseArch@beehaw.org ) 
    link
    fedilink
    English
    arrow-up
    8
    ·
    3 years ago

    Well he really could use a boost lol

    • David Gerard ( dgerard@awful.systems ) OP
      link
      fedilink
      English
      arrow-up
      8
      ·
      3 years ago

      he’s even better in the comments, absolutely unhinged

      • AcausalRobotGod ( AcausalRobotGod@awful.systems ) 
        link
        fedilink
        English
        arrow-up
        6
        ·
        3 years ago

        Maybe he’ll get to the point where he thinks you could do it by changing mouth bacteria to CRISPR your shit. Cure gum disease at the same time!

  • bitofhope ( bitofhope@awful.systems ) 
    link
    fedilink
    English
    arrow-up
    8
    ·
    3 years ago

    Credit where it’s due, I appreciate them leading with a TL;DR link to a summary. Unfortunately the summary was also too long and I didn’t read it. I’m happy for you though. Or sorry it happened.

  • Soyweiser ( Soyweiser@awful.systems ) 
    link
    fedilink
    English
    arrow-up
    7
    ·
    edit-2
    3 years ago

    LLM’s are great you doubters, look this guy even used it to get unshadowbanned on twitter.

    Re the subject at hand 250+ upvotes oof. And once I again I feel the desire to write a 'gene editing to improve intelligence is immoral because of the higher depression risk that correlates with higher intelligence. But that would backfire very quickly (esp if we hook into other reasons why very smart people with no economic resources might even be extra depressed and poof we are back at eugenics and keeping the Morlocks poor away from intelligence improvements).

    Vague association with eugenics make some academics shy away

    This guys profile:

    currently doing independent research on gene therapy with an emphasis on intelligence enhancement.

    Gosh. (I honestly had not noticed these 2 quotes before I mentioned my trollpost + risk).

    • skillissuer ( skillissuer@discuss.tchncs.de ) 
      link
      fedilink
      English
      arrow-up
      8
      ·
      3 years ago

      that’s just brave new world with extra steps

      • Soyweiser ( Soyweiser@awful.systems ) 
        link
        fedilink
        English
        arrow-up
        6
        ·
        3 years ago

        I have thought that for the distopia a lot of the right fears brave new world fits a lot better than 1984. But that is unrelated to this.

  • carlitoscohones ( carlitoscohones@awful.systems ) 
    link
    fedilink
    English
    arrow-up
    7
    ·
    3 years ago

    I clicked the original LW link (not the archive link) and got a malware warning.

    • David Gerard ( dgerard@awful.systems ) OP
      link
      fedilink
      English
      arrow-up
      11
      ·
      3 years ago

      it was warning you the page contained lesswrong rationalism

      • carlitoscohones ( carlitoscohones@awful.systems ) 
        link
        fedilink
        English
        arrow-up
        4
        ·
        3 years ago

        I just tried it again. it’s my Orbi wi-fi thing, every time I follow a link to LW - “Orbit has blocked a malware attempt.”

        • self ( self@awful.systems ) 
          link
          fedilink
          English
          arrow-up
          4
          ·
          3 years ago

          maybe whoever wrote the heuristic is also an anti-fan of rationalism and this is the form their sneering took

    • skillissuer ( skillissuer@discuss.tchncs.de ) 
      link
      fedilink
      English
      arrow-up
      3
      ·
      3 years ago

      Ripperdocs don’t want you to know this simple trick [click here]

  • Low Frequency Ovipositor ( pikesley@mastodon.me.uk ) 
    link
    fedilink
    arrow-up
    4
    ·
    3 years ago

    @dgerard god almighty there’s *so much of it*

  • HubertManne ( HubertManne@kbin.social ) 
    link
    fedilink
    arrow-up
    3
    ·
    3 years ago

    I mean personally I would fix things that are broken first. The last thing I might want to edit is anything nerve related and even then problems before enhancements. Im pretty happy with my intellect level and could not see messing with that unless it clearly was needed in the sense that I fell below one standard deviation of average intellect.

SneerClub@awful.systems

sneerclub@awful.systems

Subscribe from Remote Instance

Create a post
You are not logged in. However you can subscribe from another Fediverse account, for example Lemmy or Mastodon. To do this, paste the following into the search field of your instance: !sneerclub@awful.systems

Hurling ordure at the TREACLES, especially those closely related to LessWrong.

AI-Industrial-Complex grift is fine as long as it sufficiently relates to the AI doom from the TREACLES. (Though TechTakes may be more suitable.)

This is sneer club, not debate club. Unless it’s amusing debate.

[Especially don’t debate the race scientists, if any sneak in - we ban and delete them as unsuitable for the server.]

See our twin at Reddit

Visibility: Public
globe

This community can be federated to other instances and be posted/commented in by their users.

  • 17 users / day
  • 37 users / week
  • 96 users / month
  • 358 users / 6 months
  • 42 local subscribers
  • 1.31K subscribers
  • 517 Posts
  • 9.73K Comments
  • Modlog
  • mods:
  • self ( self@awful.systems ) 
  • blakestacey ( blakestacey@awful.systems ) 
  • David Gerard ( dgerard@awful.systems ) 
  • BE: 0.19.15
  • Modlog
  • Legal
  • Instances
  • Docs
  • Code