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ZeroCool ( ZeroCool@slrpnk.net )  to Science@mander.xyzEnglish · 3 years ago

Vaccine breakthrough means no more chasing strains

news.ucr.edu

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  • cross-posted to:
  • eric_posts_urls@discuss.online
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Vaccine breakthrough means no more chasing strains

news.ucr.edu

ZeroCool ( ZeroCool@slrpnk.net )  to Science@mander.xyzEnglish · 3 years ago
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  • cross-posted to:
  • eric_posts_urls@discuss.online
Scientists at UC Riverside have demonstrated a new, RNA-based vaccine strategy that is effective against any strain of a virus and can be used safely even by babies or the immunocompromised.
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  • Onno (VK6FLAB) ( vk6flab@lemmy.radio ) 
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    3 years ago

    Extraordinary claims require extraordinary proof.

    As it is, the first time this was posted, biologists and pharmacists discussed the merits of the claims and came to the conclusion that this was unlikely to be real.

    Specifically the approach would probably be thwarted the second time you attempted to use this method because your immune system would attack the vaccine.

    The discussion also pointed out that this was why the second dose of Astrazeneca during the COVID pandemic was less effective.

    Disclaimer: I’m not a medical professional and don’t pretend to be one online. I’m reciting from memory. YMMV.

    • ZeroCool ( ZeroCool@slrpnk.net ) OP
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      3 years ago

      Extraordinary claims require extraordinary proof.

      As it is, the first time this was posted, biologists and pharmacists discussed the merits of the claims and came to the conclusion that this was unlikely to be real.

      Link please? Kinda feel like I shouldn’t have had to ask for that based on how you chose to begin your comment but here we are.

      • Onno (VK6FLAB) ( vk6flab@lemmy.radio ) 
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        3 years ago

        https://hexbear.net/post/2315391

        • bjorney ( bjorney@lemmy.ca ) 
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          3 years ago

          So the “biologists and pharmacologists” you are citing are just armchair scientists in the Lemmy comment section

          • Umbrias ( Umbrias@beehaw.org ) 
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            3 years ago

            Unaccountable armchair ‘scientists’ on hexbear no less. Lol.

            Also once you finally get to someone discussing the content of the paper the entire tone about plausibility changes.

  • itsnicodegallo ( itsnicodegallo@lemm.ee ) 
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    3 years ago

    Note that some studies show nine mouse days are roughly equivalent to one human year.

    Excuse me?

    • jol ( jol@discuss.tchncs.de ) 
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      3 years ago

      Basically mice procrastinate much less than people.

    • runner_g ( runner_g@lemmy.blahaj.zone ) 
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      3 years ago

      Given the position of this statement in the article, I’m guessing they are trying to imply a correlation in rate of aging. Like 1 dog year = 7 human years. They are further implying that if a mouse maintains immunity for 90 days, a human would maintain immunity for 10 years.

      It should be clear that it is the reporter stating this, not the original authors of the study.

      • Pyr ( Pyr_Pressure@lemmy.ca ) 
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        3 years ago

        I’m no cell biologist but I don’t think immunity works that way. I don’t know enough to dispute it though.

        • runner_g ( runner_g@lemmy.blahaj.zone ) 
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          3 years ago

          I am a molecular biologist, and it kinda works this way. B cells are called memory cells because they hold onto that “memory” of the invader for a really long time. You probably haven’t had an MMR or a Tetanus vaccine in 10+ years because the body is really good at remembering. But we have to get flu boosters every year because the flu mutates so rapidly that traditional b cells won’t recognize the flu after a year of mutating. (RNA viruses can’t correct their mutations so they change much faster than bacteria or DNA viruses). RNAi was still pretty new when I was in school and I haven’t kept up with the research so I can’t speak to it’s effectiveness at long term immunity.

          • Pyr ( Pyr_Pressure@lemmy.ca ) 
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            3 years ago

            I know enough about that, the part I was skeptical about though was the assumption that if a mouse is immune for 90 days, a human would be immune for 10 years.

            • runner_g ( runner_g@lemmy.blahaj.zone ) 
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              3 years ago

              And you are absolutely right to be skeptical about that, that is a crazy level of extrapolation.

    • Daxtron2 ( Daxtron2@startrek.website ) 
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      3 years ago

      You’re excused

  • 1984 ( 1984@lemmy.today ) 
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    3 years ago

    I don’t vaccinate, and that is enough to get downvoted. :)

    • zoomshoes ( zoomshoes@lemmy.zip ) 
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      3 years ago

      Congratulations.

      • DragonTypeWyvern ( DragonTypeWyvern@literature.cafe ) 
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        3 years ago

        Too bad that dumbass was vaccinated as an infant

    • spartanatreyu ( spartanatreyu@programming.dev ) 
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      3 years ago

      Luckily for you, there’s not a vaccine for stupidity.

    • suodrazah ( suodrazah@aussie.zone ) 
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      3 years ago

      Don’t procreate.

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