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 Chris Remington   ( @remington@beehaw.org ) MA to Science · 9 months ago

The Return of the Dire Wolf (after 10,000 years)

time.com

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The Return of the Dire Wolf (after 10,000 years)

time.com

 Chris Remington   ( @remington@beehaw.org ) MA to Science · 9 months ago
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The Return of the Dire Wolf
time.com
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Colossal Biosciences has genetically engineered the first dire wolf to live in over 10,000 years. Here's what that means for other extinct species.

https://archive.is/UrZ0a

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  •  underscores   ( @underscores@lemmy.dbzer0.com ) 
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    9 months ago

    It’s still impressive, but they only changed 14 genes. These are much more wolf than dire wolf.

    •  HumanPenguin   ( @HumanPenguin@feddit.uk ) 
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      9 months ago

      Genuine question. How many genes were different in the original dir wolf?

      Also elsewhere said 20 genes were changed. But I’ve no reason to consider that source better then yours.

      •  underscores   ( @underscores@lemmy.dbzer0.com ) 
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        9 months ago

        Ancient DNA is pretty degraded, so it’s hard to get an exact number. It’s estimated they diverged more than 5 million years ago, so it’s probably hundreds or thousands of different genes.

        wikipedia article

        Scientists rewrote 14 key genes in gray wolf EPC cells to express 20 dire wolf traits meaning that “no ancient dire wolf DNA was actually spliced into the gray wolf’s genome.”

        •  HumanPenguin   ( @HumanPenguin@feddit.uk ) 
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          9 months ago

          Thanks.

          Also thanks for pointing out I mixed genes and traits. Was a video I saw so me missing it makes perfect sense.

    •  CanadaPlus   ( @CanadaPlus@lemmy.sdf.org ) 
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      9 months ago

      Yep, still pretty much sleazy clickbait hype. I guess actually reproducing the whole genome was too expensive.

    •  Vodulas [they/them]   ( @Vodulas@beehaw.org ) 
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      9 months ago

      Not only that, but grey wolves aren’t even the closest related existing species, and some scientists that work at Colossal wrote the study saying as much. If you want to call it a new species, sure, I could see it, but a dire wolf it is not

      •  CanadaPlus   ( @CanadaPlus@lemmy.sdf.org ) 
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        9 months ago

        Wait, which one is? Dogs?

        •  underscores   ( @underscores@lemmy.dbzer0.com ) 
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          9 months ago

          They separated pretty far back, so they’re about equally related to jackals, dogs, wild dogs, various wolf species, and coyotes.

        •  Vodulas [they/them]   ( @Vodulas@beehaw.org ) 
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          9 months ago

          African Jackals are closest based on what I have seen. Dire wolves and north American canids might share a common ancestor, though

  •  Knuschberkeks   ( @Knuschberkeks@leminal.space ) 
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    9 months ago

    why tf would you name a dire wolf Khaleesi?

    •  HumanPenguin   ( @HumanPenguin@feddit.uk ) 
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      9 months ago

      Because they only qremember 3 points about the show.

      Dire wolves where in it,

      And the 2 on Khaleesi.

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