•  ugh   ( @ugh@lemm.ee ) 
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    94 months ago

    Tylenol is easier to overdose on than NSAIDs. I really don’t think this guide is accurate. I’m really questioning the placement of cocaine and especially ketamine. Vitamin D from the sun? Lethal? I don’t believe black widows are that venomous, either. How are they even measuring this? Cocaine will give you a heart attack, Tylenol will shut down your liver, venom acts like an infection… are they basing lethal dose on how much it takes to cause some kind of fatal reaction, or under a controlled administration with a defined “fatal dose” based on a specific measurement, like damage to a human cell?

    •  blindsight   ( @blindsight@beehaw.org ) 
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      4 months ago

      I think that you’re missing the dosages. Most of these are orders of magnitude higher than the most someone would consume. Like, the caffeine value per kg of bodyweight is as much as most caffeine addicts likely have in a day. So approximately 2 orders of magnitude higher than how much we consume.

      MDMA is similar. An ecstasy pill is up to 100mg (apparently; I just looked it up), so an adult would need to pop something like 130 pills to hit the LD50.

      Acetaminophen is 500mg/pill, so that’s like a Costco-sized bottle to kill an adult.

      Vitamin D is crazy low. 1000 IU is 25 mcg, so 1000 pills is less than the LD50 for 1 kg of body weight. It’s hardly toxic at all, in the dosages we consume. You’d need to pop multiple cases of bottles of Vitamin D to overdose. All