Kind of a broad question. I wonder why people take notes - Is it for studies or learning? Is it just to remember things? Is it to make your own map of your knowledge? Is it because you just want a place to vent out your feelings into the void?
What do you use to accomplish that? App? Paper? A chat room?
I got note taking pounded into my head in middle and high school (though I don’t use their required method to do so anymore), so studies and learning are pretty much the same for me. After that, I find that taking notes engages me with the material more, and it’s more likely to stick. If I’m reading dead trees and it’s my copy, I take notes in the margins and annotate the text. If not, I have a personal wiki that I store all of my notes in.